Current Studies

Ongoing Study Opportunities

Ever think about trying a different method of treatment for your current health status? Great Lakes Gastroenterology Research has multiple study opportunities that you may be interesting in joining! Check back frequently to view the updated list of clinical trials, as new studies are added to the database monthly. You can become a potential study participant by registering today! Studies are listed below by therapeutic area and physician. If you have any additional questions about one of the studies, please contact us.

GASTROENTEROLOGY

Studies related to gastrointestinal organs and related diseases, including the digestive tract, liver, and the pancreas. Examples of these studies include: Constipation, Crohn’s Disease, Diarrhea, Gall-bladder Disease, Heartburn, Hemorrhoids, Irritable Bowel Syndrome (IBS), Ulcers, and various other conditions.

Bowel Preparation

A study to evaluate the efficacy of a potential study drug for bowel preparation prior to a scheduled colonoscopy.

  • Between 18-85 years; no bowel obstructions
  • No IBD with bowel resection history, active inflammation or stricture
  • No significant GI surgeries
  • Must have stable diuretics, anti-hypertensive, ACE inhibitors, ARBs and chronic NSAIDs
  • No uncontrolled hypertension, no severe renal insufficiency, hepatic insufficiency, cardiac insufficiency
  • No insulin therapy or tricyclic antidepressants

Call Us
440.205.1225
Email Us
chrisp@glmrx.com
Online
Please fill out our patient recruitment form.

Celiac Disease

Study to access investigational agent for patients with symptoms on a Gluten Free Diet.

  • ≥18 years old.
  • Celiac diagnosis ≥ 6 months confirmed by biopsy and serology.
  • Positive for HLA-DQ2 or HLA-DQ8.
  • Has GI symptoms (pain, cramping diarrhea, etc.) at least once/week or 4 times/month despite gluten free diet for at least 6 months prior to screening.
  • No IBD, IBS, gastroparesis, lupus.
  • No Type 1 diabetes. No HbA1c > 8.5%.
  • No cancer in past 5 years.

Call Kelli Holcknecht
(440) 205-1225 x 267
Email
kholcknecht@thectnx.com
Online
Please fill out our patient recruitment form.

Chrohns Disease

A study to evaluate the efficacy of a potential study drug to reduce inflammation in the digestive system.

  • 18 Years of age or older
  • List of current medications must be evaluated by a study coordinator for qualification

Call Kelli Holcknecht
(440) 205-1225 x 267
Email
kholcknecht@thectnx.com
Online
Please fill out our patient recruitment form.

CRC Screening

Developing new blood tests to detect Colorectal Cancer.

  • Age 40+. Screening colonoscopy—no scope in past 9 years.
  • No positive Cologuard or FIT in past 2 years.
  • No hx of CRC, FAP, Lynch, other hereditary cancer syndromes.
  • No IBD.

Call Us
440.205.1225
Email Us
chrisp@glmrx.com
Online
Please fill out our patient recruitment form.

Eosinophilic Esophagitis/Eosinophilic gastroenteritis

Study to assess the efficacy and safety of investigational agent, given monthly for 6 doses, in patients with moderately to severely active Eosinophilic Gastritis and/or Eosinophilic Duodenitis (formerly referred to as Eosinophilic Gastroenteritis) who have an inadequate response with, lost response to, or were intolerant to standard therapies.

  • 18 – 80 years old.
  • Baseline EDG more than 30 eosinophils/hpf in 5 hpf, inadequate or loss of response to standard therapies: PPI, antihistamines, systemic or topical corticosteroids, and diet.
  • No hx of corticosteroids 4 weeks prior, no change in PPI, leukotrienes, or diet 4 weeks prior.
  • No hx of IBD, celiac, achalasia, or esophageal

Call Kelli Holcknecht
(440) 205-1225 x 267
Email
kholcknecht@thectnx.com
Online
Please fill out our patient recruitment form.

Irritable Bowel Syndrome

The purpose of this study is to determine whether the investigational agent is a safe and effective treatment for abdominal pain in participants with irritable bowel syndrome (IBS).

  • Age 18-70.
  • IBS-C or IBS-D w/ abdominal pain.
  • No IBD or Celiac, no hx of CRC or diverticulitis.
  • No hx of GI stricture, perforation, surgery.
  • No cholecystectomy.
  • No diabetes.
  • No orthostatic hypotension or uncontrolled hypertension.
  • No moderate or strong CYP3A4 inhibitors/inducers (e.g. fluoxetine, alprazolam, sertraline, atorvastatin, prednisone).
  • No positive hx of occult blood or bacterial tests in past 6 months.

Call Kelli Holcknecht
(440) 205-1225 x 267
Email
kholcknecht@thectnx.com
Online
Please fill out our patient recruitment form.

Ulcerative Colitis

A study to evaluate the efficacy of a potential study drug to reduce inflammation in the digestive system.

  • 18 Years of age or older
  • List of current medications must be evaluated by a study coordinator for qualification

Call Kelli Holcknecht
(440) 205-1225 x 267
Email
kholcknecht@thectnx.com
Online
Please fill out our patient recruitment form.

  • Register for a TRIAL TODAY


    Ever think about trying a different method of treatment for your current health status? Great Lakes Gastroenterology Research has multiple study opportunities that you may be interested in joining!

  • REGISTER NOW